Cyclopamine
APC-587
Cyclopamine
Cat. No.
APC-587
CAS No.
4449-51-8
MF
C27H41NO2
MW
411.62
Cyclopamine is a Hedgehog (Hh) pathway antagonist.
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Description
Storage and Shipping
References
Product Name
CAS No.
4449-51-8
MF
C27H41NO2
MW
411.62
Specification
98%
Research Area
Anticancer, anti-proliferative,pro-apoptotic
Description
Cyclopamine is a Hedgehog (Hh) pathway antagonist. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat
References
[1]. Peukert S, et al. Identification and structure-activity relationships of ortho-biphenyl carboxamides as potent Smoothened antagonists inhibiting the Hedgehog signaling pathway. Bioorg Med Chem Lett, 2009, 19(2), 328-331.
[2]. Berman DM, et al. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature, 2003, 425(6960), 846-851.
[3]. Thayer SP, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature, 2003, 425(6960), 851-856.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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